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Protein Coding Gene : Eed embryonic ectoderm development

Primary Identifier  MGI:95286 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  13626
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Enables chromatin binding activity and enzyme activator activity. Contributes to promoter-specific chromatin binding activity. Involved in facultative heterochromatin formation and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; genomic imprinting; and regulation of adaxial/abaxial pattern formation. Located in pronucleus and sex chromatin. Part of ESC/E(Z) complex and chromatin silencing complex. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; extraembryonic component; and genitourinary system. Orthologous to human EED (embryonic ectoderm development).
PHENOTYPE: Homozygous mutant mice are dwarfed and their coat color is dilute. [provided by MGI curators]
  • synonyms:
  • embryonic ectoderm development,
  • MGI:3584396,
  • predicted gene, ENSMUSG00000039373,
  • MGD-MRK-11693,
  • MGD-MRK-9305,
  • Eed,
  • MGD-MRK-11725,
  • MGI:3641985,
  • ENSMUSG00000039373,
  • lethal, Chr 7, Rinchik 5,
  • MGI:96737,
  • l(7)5Rn,
  • l7Rn5

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

33 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For