| Primary Identifier | MGI:95286 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 13626 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables chromatin binding activity and enzyme activator activity. Contributes to promoter-specific chromatin binding activity. Involved in facultative heterochromatin formation and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; genomic imprinting; and regulation of adaxial/abaxial pattern formation. Located in pronucleus and sex chromatin. Part of ESC/E(Z) complex and chromatin silencing complex. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; extraembryonic component; and genitourinary system. Orthologous to human EED (embryonic ectoderm development). PHENOTYPE: Homozygous mutant mice are dwarfed and their coat color is dilute. [provided by MGI curators] |