| Primary Identifier | MGI:2444036 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 100043597 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable ATP hydrolysis activity; histone binding activity; and transcription coactivator activity. Predicted to contribute to ATP-dependent chromatin remodeler activity. Predicted to be involved in cAMP/PKA signal transduction; chromatin remodeling; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nuclear body and perinuclear region of cytoplasm. Predicted to be part of Swr1 complex. Predicted to be active in nucleus. Is expressed in several structures, including 2-cell stage conceptus; 4-8 cell stage conceptus; blastocyst-stage conceptus; cerebral cortex; and oocyte. Human ortholog(s) of this gene implicated in Floating-Harbor syndrome. Orthologous to human SRCAP (Snf2 related CREBBP activator protein). PHENOTYPE: Mice homozygous for a null allele show impaired blastocyst development at E3.5 and early embryonic lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
