| Primary Identifier | MGI:1861718 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 56843 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables calcium-activated cation channel activity; potassium channel activity; and sodium channel activity. Involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus. Acts upstream of or within monoatomic ion transmembrane transport. Predicted to be located in dendrite and neuronal cell body. Predicted to be active in plasma membrane. Is expressed in several structures, including ganglia; genitourinary system; gut; hemolymphoid system gland; and liver and biliary system. Orthologous to human TRPM5 (transient receptor potential cation channel subfamily M member 5). PHENOTYPE: Homozygous mutant mice demonstrate abnormal taste perception, responding to sour and salty stimuli but not to sweet, or bitter stimuli. [provided by MGI curators] |