| Primary Identifier | MGI:3033142 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 211578 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables G protein-coupled peptide receptor activity. Involved in several processes, including angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure; negative regulation of cardiac muscle hypertrophy; and sensory perception of itch. Is active in plasma membrane. Is expressed in genitourinary system; nervous system; and skin. Used to study dilated cardiomyopathy. Orthologous to human MRGPRD (MAS related GPR family member D). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased sensitivity to cold, heat, and mechanical stimuli. Mice for another null allele exhibit dilated cardiomypathy and cardiac dysfunction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
