| Primary Identifier | MGI:1345183 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 23965 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including homophilic cell-cell adhesion; regulation of homophilic cell adhesion; and synaptic membrane adhesion. Located in plasma membrane. Is active in glutamatergic synapse and presynaptic active zone membrane. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human TENM3 (teneurin transmembrane protein 3). PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. A heterozygous p.Q2665P mutation conditionally expressed in embryonic limb buds leads to delayed chondrogenesis in left hip and shoulder joints. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
