Primary Identifier | MGI:1921449 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 74199 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glycosaminoglycan binding activity. Involved in spinal cord development. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in interstitial matrix. Is expressed in several structures, including cranium; ganglia; sensory organ; ventral grey horn; and ventricular layer. Orthologous to human VIT (vitrin). PHENOTYPE: Embryos homozygous for a knock-out allele show decreased spinal cord size associated with reduced cell proliferation and altered cell differentiation in the central canal. [provided by MGI curators] |