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Protein Coding Gene : Sik2 salt inducible kinase 2

Primary Identifier  MGI:2445031 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  235344
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0)

Enables ATP binding activity; magnesium ion binding activity; and protein kinase activity. Involved in intracellular signal transduction; negative regulation of transcription from RNA polymerase II promoter by glucose; and regulation of insulin receptor signaling pathway. Acts upstream of or within insulin receptor signaling pathway and protein phosphorylation. Located in cytoplasm and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and heart. Orthologous to human SIK2 (salt inducible kinase 2).
PHENOTYPE: Mice heterozygous for a knock-out allele exhibit darkened hair color in an agouti background. [provided by MGI curators]
  • synonyms:
  • Sik2,
  • SNF1-like kinase 2,
  • salt induceable kinase 2,
  • RIKEN cDNA G630080D20 gene,
  • salt inducible kinase 2,
  • G630080D20Rik,
  • Snf1lk2

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Proteins

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