| Primary Identifier | MGI:2445031 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 235344 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables ATP binding activity; magnesium ion binding activity; and protein kinase activity. Involved in intracellular signal transduction; negative regulation of transcription from RNA polymerase II promoter by glucose; and regulation of insulin receptor signaling pathway. Acts upstream of or within insulin receptor signaling pathway and protein phosphorylation. Located in cytoplasm and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and heart. Orthologous to human SIK2 (salt inducible kinase 2). PHENOTYPE: Mice heterozygous for a knock-out allele exhibit darkened hair color in an agouti background. [provided by MGI curators] |