| Primary Identifier | MGI:2445221 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 235505 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable endopeptidase inhibitor activity. Acts upstream of or within several processes, including negative regulation of keratinocyte proliferation; osteoclast fusion; and regulation of keratinocyte differentiation. Located in extracellular region. Is expressed in brain; notochord; and nucleus pulposus. Orthologous to human CD109 (CD109 molecule). PHENOTYPE: Mice homozygous for a null mutation display epidermal hyperplasia and thickening, sebaceous gland hyperplasia and transient impairment of hair growth. [provided by MGI curators] |