Primary Identifier | MGI:1913731 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 66481 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation; endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in 1-cell stage embryo; 2-cell stage embryo; and 4-cell stage embryo. Orthologous to human RPS21 (ribosomal protein S21). PHENOTYPE: Mice heterozygous for a null allele exhibit reduced growth, premature death, and impaired male fertility. [provided by MGI curators] |