Primary Identifier | MGI:1346316 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 24047 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables CCR7 chemokine receptor binding activity and chemokine activity. Involved in several processes, including positive regulation of T cell activation; positive regulation of cellular component organization; and positive regulation of macromolecule biosynthetic process. Located in external side of plasma membrane. Is expressed in Peyer's patch; inguinal lymph node; thymus; and thymus primordium. Orthologous to human CCL19 (C-C motif chemokine ligand 19). PHENOTYPE: Homozygous mutation of this gene results in reduced T cell numbers. [provided by MGI curators] |