| Primary Identifier | MGI:97143 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 17357 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity. Acts upstream of or within positive regulation of cell population proliferation. Predicted to be located in cytoskeleton. Predicted to be active in presynaptic cytosol; presynaptic membrane; and synaptic vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human MARCKSL1 (MARCKS like 1). PHENOTYPE: Homozygotes for a targeted null mutation exhibit neural tube defects resulting in anencephaly, spina bifida, abnormal brain development, tail malformations, and neonatal lethality. A small percentage of heterozygotes also show neural tube defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
