| Primary Identifier | MGI:95316 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 13706 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase activity. Predicted to be involved in several processes, including insulin catabolic process; regulation of insulin secretion; and response to insulin. Located in collagen-containing extracellular matrix. Is expressed in bone marrow; liver; pancreas; and pancreatic acinus. Human ortholog(s) of this gene implicated in abdominal obesity-metabolic syndrome 4. Orthologous to several human genes including CELA2A (chymotrypsin like elastase 2A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered cardiac sympathovagal balance, reduced heart rate, and decreased cardiac output, stroke volume and heart ventricular size. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
