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Protein Coding Gene : Oas1d 2'-5' oligoadenylate synthetase 1D
Primary Identifier  MGI:2140770 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  100535
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables double-stranded RNA binding activity and enzyme inhibitor activity. Acts upstream of or within ovarian follicle development and ovulation from ovarian follicle. Located in cytoplasm. Is expressed in several structures, including genitourinary system; heart; liver; lung; and thymus. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1).
PHENOTYPE: Homozygous null females exhibit reduced fertility due to defects in ovarian follicle development and decreased efficiency of ovulation. [provided by MGI curators]
  • synonyms:
  • AA536864,
  • expressed sequence AA536864,
  • C85127,
  • Oas1d,
  • expressed sequence C85127,
  • MGI:2141327,
  • 2'-5' oligoadenylate synthetase 1D
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