Primary Identifier | MGI:96178 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 15403 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within anterior/posterior pattern specification and embryonic skeletal system development. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb; and vertebral cartilage condensation. Orthologous to human HOXA6 (homeobox A6). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile but show posterior transformations of the seventh cervical vertebra to the first thoracic vertebra with incomplete penetrance and variable expressivity. [provided by MGI curators] |