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Protein Coding Gene : Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
Primary Identifier  MGI:1914928 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  67678
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable U6 snRNA 3'-end binding activity. Predicted to be involved in P-body assembly and mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of Lsm1-7-Pat1 complex; Lsm2-8 complex; and nucleus. Predicted to be active in P-body. Is expressed in central nervous system and sensory organ. Orthologous to human LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated).
PHENOTYPE: MIce homozygous for an allele that only expresses variant 1 exhibit decreased susceptibility to VSV and influenza infection. [provided by MGI curators]
  • synonyms:
  • 1010001J12Rik,
  • MGI:2442209,
  • LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated,
  • RIKEN cDNA 2610005D18 gene,
  • 2610005D18Rik,
  • RIKEN cDNA 6030401D18 gene,
  • 6030401D18Rik,
  • SMX4,
  • RIKEN cDNA 1010001J12 gene,
  • MGI:1917279,
  • USS2,
  • Lsm3
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Features --> Cross References

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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