| Primary Identifier | MGI:1889005 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 108017 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ATPase binding activity. Predicted to be involved in inorganic cation transmembrane transport and positive regulation of sodium ion export across plasma membrane. Predicted to be located in basolateral plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Orthologous to human FXYD4 (FXYD domain containing ion transport regulator 4). PHENOTYPE: Mice homozygous for a targeted null mutation are viable and fertile but exhibit a significant increase in urine volume (and water intake) under Na+ deprivation and K+ loading, as well as lethality after a combination of high-K+ intake and furosemide injection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
