| Primary Identifier | MGI:1351899 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 28253 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable oligopeptide transmembrane transporter activity; organic anion transmembrane transporter activity; and prostaglandin transmembrane transporter activity. Predicted to be involved in bile acid and bile salt transport; oligopeptide transport; and sodium-independent organic anion transport. Predicted to be located in basal plasma membrane. Predicted to be active in basolateral plasma membrane. Is expressed in liver. Human ortholog(s) of this gene implicated in bilirubin metabolic disorder and gastrointestinal stromal tumor. Orthologous to human SLCO1B1 (solute carrier organic anion transporter family member 1B1); SLCO1B3 (solute carrier organic anion transporter family member 1B3); and SLCO1B7 (solute carrier organic anion transporter family member 1B7 (putative)). PHENOTYPE: Mice homozygous for a null mutation display slight abnormalities in blood chemistry and are resistant to injury induced by some classes of hepatotoxins. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
