| Primary Identifier | MGI:1888998 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 57775 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cysteine-type endopeptidase activity. Involved in several processes, including positive regulation of type I interferon-mediated signaling pathway; protein K48-linked deubiquitination; and protein stabilization. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain; limb bud; testis; and trunk. Orthologous to human USP29 (ubiquitin specific peptidase 29). PHENOTYPE: Paternal inheritance of a KO allele results in decreased birth weight and changes in chromosome methylation. Fathers carrying a KO allele sire smaller litters. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
