| Primary Identifier | MGI:1351612 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 27358 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable CCR6 chemokine receptor binding activity; chemoattractant activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Acts upstream of or within defense response to bacterium. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in skin. Orthologous to human DEFB4A (defensin beta 4A) and DEFB4B (defensin beta 4B). PHENOTYPE: Mice homozygous for a knock-out allele exhibits increased susceptibility to P. aeruginosa- or F. solani-induced keratitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
