| Primary Identifier | MGI:2446460 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 234129 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Predicted to be active in cytosol. Is expressed in brain; eye; future spinal cord; surface ectoderm; and testis. Orthologous to several human genes including TPTE2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2). PHENOTYPE: Male mice homozygous for a null allele exhibit impaired fertilization associated with loss of sperm midpiece flexibility and asthenozoospermia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
