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Protein Coding Gene : Ces2a carboxylesterase 2A
Primary Identifier  MGI:2142491 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  102022
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables carboxylesterase activity. Acts upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in liver. Orthologous to human CES2 (carboxylesterase 2).
PHENOTYPE: Knock-out mice are obese, with increased adiposity, and high-fat diet feeding exacerbates hepatic steatosis and impairs glucose homeostasis, with insulin resistance and glucose intolerance. [provided by MGI curators]
  • synonyms:
  • AI266984,
  • RIKEN cDNA 9130231C15 gene,
  • expressed sequence AI266984,
  • Ces2a,
  • carboxylesterase 6,
  • carboxylesterase 2A,
  • Ces6,
  • 9130231C15Rik
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