| Primary Identifier | MGI:3619412 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 723870 |
| Mgi Type | miRNA gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including erythrocyte differentiation; mitochondrial ATP synthesis coupled electron transport; and negative regulation of gene expression. Acts upstream of or within several processes, including cellular hyperosmotic salinity response; cellular response to estrogen stimulus; and sensory perception of sound. Located in extracellular exosome. Part of RISC complex. Is expressed in bone marrow; liver; vascular element; and yolk sac. Orthologous to human MIR451A (microRNA 451a). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired terminal erythropoeisis associated with decreased erythrocyte numbers, decreased hematocrit, increased red blood cell distribution width, enlarged spleen, and increased erythroid progenitor cells inthe spleen. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
