Primary Identifier | MGI:97814 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 19270 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and protein tyrosine phosphatase activity. Predicted to be involved in several processes, including negative regulation of epithelial cell migration; negative regulation of neuron projection development; and neuron projection development. Predicted to be located in extracellular space. Is expressed in several structures, including central nervous system and retina. Orthologous to human PTPRG (protein tyrosine phosphatase receptor type G). PHENOTYPE: Mice homozygous for a knock-out allele are overtly normal but exhibit minor behavioral changes including specific motor deficits, reduced latency to react in the tail flick test, enhanced sensory processing for acoustic stimuli, and reduced performance with cued fear conditioning. [provided by MGI curators] |