| Primary Identifier | MGI:2386306 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 223650 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables keratin filament binding activity. Involved in several processes, including intermediate filament bundle assembly; negative regulation of keratinocyte migration; and regulation of epithelial cell proliferation. Located in several cellular components, including apicolateral plasma membrane; basal part of cell; and cell-cell junction. Colocalizes with keratin filament. Is expressed in several structures, including alimentary system; liver and biliary system; respiratory system; sensory organ; and skin. Orthologous to human EPPK1 (epiplakin 1). PHENOTYPE: Mice homozygous for a null allele exhbit normal skin morphology. Mice homozygous for a reporter knock-in allele exhibit enhanced wound healing associated with increased keratinocyte migration. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
