| Primary Identifier | MGI:2676278 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 239611 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables hydroxyapatite binding activity. Acts upstream of or within several processes, including exocrine system development; hemopoiesis; and lymphocyte proliferation. Predicted to be located in extracellular region. Is expressed in sublingual gland; sublingual gland epithelium; and submandibular duct. Used to study Sjogren's syndrome. Orthologous to human MUC19 (mucin 19, oligomeric (gene/pseudogene)). PHENOTYPE: Mice homozygous for this spontaneous mutation show a partially arrested mucous cell differentiation of the sublingual glands. Severe inflammatory lesions resembling Sjogren's syndrome develop spontaneously in salivary and lacrimal glands of neonatally thymectomized mutants without any immunization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
