| Primary Identifier | MGI:95937 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 68395 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable beta-2-microglobulin binding activity; peptide antigen binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Predicted to be located in cell surface. Predicted to be part of MHC class I protein complex. Predicted to be active in external side of plasma membrane and extracellular space. Is expressed in spleen. Orthologous to human HLA-H (major histocompatibility complex, class I, H (pseudogene)). PHENOTYPE: This locus controls a lymphocyte antigen recognized by a monoclonal antibody. It is present on T-cells of lymph node, spleen and bone marrow, but absent from thymus. Strains positive for antigen are C57BL/6, C57BL/10, C57L, 129, NZB and SJL; other strains tested were negative. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
