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Protein Coding Gene : Rsc1a1 regulatory solute carrier protein, family 1, member 1
Primary Identifier  MGI:3526447 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  69994
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable sodium channel inhibitor activity. Acts upstream of or within intestinal absorption and negative regulation of protein localization to plasma membrane. Located in brush border and membrane. Used to study obesity. Orthologous to human RSC1A1 (regulator of solute carriers 1).
PHENOTYPE: Homozygous null mice develop obesity and exhibit increased serum cholesterol and leptin levels and increased absorption of D-glucose in the small intestine. [provided by MGI curators]
  • synonyms:
  • MGI:3707227,
  • Rsc1a1,
  • RS1,
  • mRS1,
  • regulatory solute carrier protein, family 1, member 1,
  • OTTMUSG00000010365,
  • predicted gene, OTTMUSG00000010365
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