Primary Identifier | MGI:5596028 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 102640920 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatase binding activity and signaling receptor activity. Predicted to be involved in negative regulation of T cell receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human PVRIG (PVR related immunoglobulin domain containing). PHENOTYPE: Mice homozygous for a null allele exhibit increased CD8+ effector T cell function and growth inhibition of implanted tumor cells. [provided by MGI curators] |