| Primary Identifier | MGI:892020 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 16622 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables serine-type endopeptidase activity. Acts upstream of or within proteolysis. Predicted to be located in acrosomal vesicle; apical part of cell; and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in extracellular space and secretory granule. Is expressed in metanephros and salivary gland. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1). PHENOTYPE: Mice homozygous for a null mutation display normal fertility, growth, and submandibular gland morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
