Primary Identifier | MGI:1920982 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 73732 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within negative regulation of epithelial cell proliferation; negative regulation of interleukin-6 production; and negative regulation of wound healing. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; mesothelium; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human MUC16 (mucin 16, cell surface associated). PHENOTYPE: Homozygous null mice are viable and fertile with no gross histological abnormalities. Homozygous male mice father larger litters when crossed to wild-type females. [provided by MGI curators] |