Primary Identifier | MGI:2661338 | Organism | mouse, laboratory |
Chromosome | 9 | Mgi Type | polymorphic pseudogene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Is expressed in olfactory epithelium. Orthologous to human OR8A1 (olfactory receptor family 8 subfamily A member 1). PHENOTYPE: Deletion of the coding region causes olfactory sensory neurons to coexpress other odorant receptor (ORs) that function in axonal identity. A drastic reduction in OR protein level causes axonal coalescence into new remote glomeruli. Chimeric ORs and ORs with minor mutations preclude axon outgrowth. [provided by MGI curators] |