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ncRNA Gene : mt-Tl1 mitochondrially encoded tRNA leucine 1
Primary Identifier  MGI:102482 Organism  mouse, laboratory
Chromosome  MT NCBI Gene Number  17735
Mgi Type  tRNA gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable triplet codon-amino acid adaptor activity. Predicted to act upstream of or within translational elongation. Predicted to be located in mitochondrion. Used to study MELAS syndrome. Human ortholog(s) of this gene implicated in cardiomyopathy. Orthologous to human MT-TL1 (mitochondrially encoded tRNA-Leu (UUA/G) 1).
PHENOTYPE: Mice carrying a high percentage of mitochondria carrying a point mutation display mitochondrial dysfunction and age-related metabolic phenotypes. [provided by MGI curators]
  • synonyms:
  • mitochondrially encoded tRNA leucine 1,
  • tRNA,
  • mt-Tl1,
  • tRNA Leu_1,
  • MGD-MRK-19319,
  • TrnrL1 tRNA,
  • tRNA Leu
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