Primary Identifier | MGI:96090 | Organism | mouse, laboratory |
Chromosome | X | NCBI Gene Number | 107626 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables acetylserotonin O-methyltransferase activity. Acts upstream of or within melatonin biosynthetic process and negative regulation of male gonad development. Orthologous to human ASMT (acetylserotonin O-methyltransferase). PHENOTYPE: Pineal melatonin synthesis requires enzymes encoded by Asmt and Aanat. C57BL/6, BALB/c, AKR/J, NZB/Bl, IS/Cam, and CAST/Ei carry the a allele of Asmt and lack melatonin. SK/Cam, SF/Cam, PERU, and FDS carry the b allele and have normal melatonin levels. [provided by MGI curators] |