First Author | Salbaum JM | Year | 1998 |
Journal | Mech Dev | Volume | 71 |
Issue | 1-2 | Pages | 201-4 |
PubMed ID | 9507132 | Mgi Jnum | J:46645 |
Mgi Id | MGI:1201723 | Doi | 10.1016/s0925-4773(98)00005-7 |
Citation | Salbaum JM (1998) Punc, a novel mouse gene of the immunoglobulin superfamily, is expressed predominantly in the developing nervous system. Mech Dev 71(1-2):201-4 |
abstractText | A search for genes regulated by the LlM/homeodomain transcription factor islet-1 during development identified the novel mouse gene punc (putative neuronal cell adhesion molecule). Punc is a member of the immunoglobulin superfamily, exhibits a novel configuration of four immunoglobulin domains and two fibronectin-type III repeats, and resembles proteins involved in axon guidance. Punc expression in the embryo occurs in restricted patterns in both the nervous system and limb mesoderm. A sharp decrease in punc expression after embryonic day 11.5 suggests a function for punc early in mouse embryogenesis. |