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Publication : Punc, a novel mouse gene of the immunoglobulin superfamily, is expressed predominantly in the developing nervous system.

First Author  Salbaum JM Year  1998
Journal  Mech Dev Volume  71
Issue  1-2 Pages  201-4
PubMed ID  9507132 Mgi Jnum  J:46645
Mgi Id  MGI:1201723 Doi  10.1016/s0925-4773(98)00005-7
Citation  Salbaum JM (1998) Punc, a novel mouse gene of the immunoglobulin superfamily, is expressed predominantly in the developing nervous system. Mech Dev 71(1-2):201-4
abstractText  A search for genes regulated by the LlM/homeodomain transcription factor islet-1 during development identified the novel mouse gene punc (putative neuronal cell adhesion molecule). Punc is a member of the immunoglobulin superfamily, exhibits a novel configuration of four immunoglobulin domains and two fibronectin-type III repeats, and resembles proteins involved in axon guidance. Punc expression in the embryo occurs in restricted patterns in both the nervous system and limb mesoderm. A sharp decrease in punc expression after embryonic day 11.5 suggests a function for punc early in mouse embryogenesis.
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