First Author | Savary S | Year | 1997 |
Journal | Genomics | Volume | 41 |
Issue | 2 | Pages | 275-8 |
PubMed ID | 9143506 | Mgi Jnum | J:39831 |
Mgi Id | MGI:87180 | Doi | 10.1006/geno.1997.4658 |
Citation | Savary S, et al. (1997) Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human. Genomics 41(2):275-8 |
abstractText | We report here on the identification and genomic mapping of a novel member of the family of the ATP-binding cassette (ABC) transporters, ABC7, conserved in mouse and in humans. The ABC7 gene encodes a protein with the typical features of half-transporters, such as those involved in translocation of antigenic peptides or in peroxisomal disorders. ABC7 shows a ubiquitous expression pattern and maps to the X chromosome both in mouse and in humans. The high sequence similarity to those of two yeast half-transporters supports once again the extreme evolutionary conservation of this family of proteins. (C) 1997 Academic Press. |