First Author | Batra RS | Year | 1996 |
Journal | FEBS Lett | Volume | 393 |
Issue | 2-3 | Pages | 167-73 |
PubMed ID | 8814283 | Mgi Jnum | J:35365 |
Mgi Id | MGI:82814 | Doi | 10.1016/0014-5793(96)00878-2 |
Citation | Batra RS, et al. (1996) Molecular cloning and tissue-specific expression of mouse kidney 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. FEBS Lett 393(2-3):167-73 |
abstractText | A 1932 bp cDNA clone encoding a novel isozyme of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (PFK-2/ FBPase-2) was isolated from a mouse kidney cDNA library. The sequence encodes 519 amino acids and, based on homology to rat heart genomic sequence, appears to be the product of alternative splicing from PFK-2/FBPase-2 gene B with an extended version of exon 15. Northern blot analysis indicated that this clone corresponds to an 8 kb mRNA expressed in multiple tissues, with the strongest signal in kidney, and detects several additional transcripts which may be alternatively spliced from gene B. |