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Publication : Molecular cloning and tissue-specific expression of mouse kidney 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

First Author  Batra RS Year  1996
Journal  FEBS Lett Volume  393
Issue  2-3 Pages  167-73
PubMed ID  8814283 Mgi Jnum  J:35365
Mgi Id  MGI:82814 Doi  10.1016/0014-5793(96)00878-2
Citation  Batra RS, et al. (1996) Molecular cloning and tissue-specific expression of mouse kidney 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. FEBS Lett 393(2-3):167-73
abstractText  A 1932 bp cDNA clone encoding a novel isozyme of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (PFK-2/ FBPase-2) was isolated from a mouse kidney cDNA library. The sequence encodes 519 amino acids and, based on homology to rat heart genomic sequence, appears to be the product of alternative splicing from PFK-2/FBPase-2 gene B with an extended version of exon 15. Northern blot analysis indicated that this clone corresponds to an 8 kb mRNA expressed in multiple tissues, with the strongest signal in kidney, and detects several additional transcripts which may be alternatively spliced from gene B.
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