First Author | Sifers RN | Year | 1990 |
Journal | Genomics | Volume | 6 |
Issue | 1 | Pages | 100-4 |
PubMed ID | 2303252 | Mgi Jnum | J:10300 |
Mgi Id | MGI:58753 | Doi | 10.1016/0888-7543(90)90453-2 |
Citation | Sifers RN, et al. (1990) Complete cDNA sequence and chromosomal localization of mouse alpha 1-antitrypsin. Genomics 6(1):100-4 |
abstractText | A cDNA encoding the complete open reading frame of murine alpha 1-antitrypsin has been cloned and sequenced. The nucleic acid and predicted amino acid sequences show homology to human alpha 1-antitrypsin and demonstrate the preservation of critical structural determinants for intracellular targeting, carbohydrate attachment, and catalytic function. The alpha 1-antitrypsin gene locus (Aat) has been localized on murine chromosome 12E----F by in situ hybridization. |