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Publication : Complete cDNA sequence and chromosomal localization of mouse alpha 1-antitrypsin.

First Author  Sifers RN Year  1990
Journal  Genomics Volume  6
Issue  1 Pages  100-4
PubMed ID  2303252 Mgi Jnum  J:10300
Mgi Id  MGI:58753 Doi  10.1016/0888-7543(90)90453-2
Citation  Sifers RN, et al. (1990) Complete cDNA sequence and chromosomal localization of mouse alpha 1-antitrypsin. Genomics 6(1):100-4
abstractText  A cDNA encoding the complete open reading frame of murine alpha 1-antitrypsin has been cloned and sequenced. The nucleic acid and predicted amino acid sequences show homology to human alpha 1-antitrypsin and demonstrate the preservation of critical structural determinants for intracellular targeting, carbohydrate attachment, and catalytic function. The alpha 1-antitrypsin gene locus (Aat) has been localized on murine chromosome 12E----F by in situ hybridization.
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