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Publication : The sequence of 5' flanking DNA from the mouse 11 beta-hydroxysteroid dehydrogenase type 1 gene and analysis of putative transcription factor binding sites.

First Author  Voice MW Year  1996
Journal  Gene Volume  181
Issue  1-2 Pages  233-5
PubMed ID  8973338 Mgi Jnum  J:37988
Mgi Id  MGI:85381 Doi  10.1016/s0378-1119(96)00490-8
Citation  Voice MW, et al. (1996) The sequence of 5' flanking DNA from the mouse 11 beta-hydroxysteroid dehydrogenase type 1 gene and analysis of putative transcription factor binding sites. Gene 181(1-2):233-5
abstractText  11 beta-Hydroxysteroid dehydrogenase type 1 (E.C. 1.1.1.146) (11 beta-HSD 1) is a key enzyme in the metabolism of glucocorticoids, catalysing their interconversion with physiologically inert 11-keto metabolites. To identify transcription factors which may be involved in the regulation of expression of mouse 11 beta-HSD 1 we have isolated and sequenced the 5' flanking DNA to 900 bp upstream from the major transcription start site.
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