First Author | Voice MW | Year | 1996 |
Journal | Gene | Volume | 181 |
Issue | 1-2 | Pages | 233-5 |
PubMed ID | 8973338 | Mgi Jnum | J:37988 |
Mgi Id | MGI:85381 | Doi | 10.1016/s0378-1119(96)00490-8 |
Citation | Voice MW, et al. (1996) The sequence of 5' flanking DNA from the mouse 11 beta-hydroxysteroid dehydrogenase type 1 gene and analysis of putative transcription factor binding sites. Gene 181(1-2):233-5 |
abstractText | 11 beta-Hydroxysteroid dehydrogenase type 1 (E.C. 1.1.1.146) (11 beta-HSD 1) is a key enzyme in the metabolism of glucocorticoids, catalysing their interconversion with physiologically inert 11-keto metabolites. To identify transcription factors which may be involved in the regulation of expression of mouse 11 beta-HSD 1 we have isolated and sequenced the 5' flanking DNA to 900 bp upstream from the major transcription start site. |