First Author | Feng JQ | Year | 1994 |
Journal | Biochim Biophys Acta | Volume | 1218 |
Issue | 2 | Pages | 221-4 |
PubMed ID | 8018727 | Mgi Jnum | J:18993 |
Mgi Id | MGI:67224 | Doi | 10.1016/0167-4781(94)90017-5 |
Citation | Feng JQ, et al. (1994) Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes. Biochim Biophys Acta 1218(2):221-4 |
abstractText | Screening of a mouse spleen genomic DNA library with mouse BMP-4 and BMP-2 cDNA probes led to the isolation of mouse BMP-2 gene. This gene contains approximately 11 kb transcription unit and 3 exons. The deduced protein has 394 amino acids. The C-terminal amino acid mature coding region is identical to that of the human BMP-2. Comparison of mouse BMP-2 and BMP-4 gene shows little similarity in exon/intron structure, although the mature coding peptide regions of both genes share over 90% identity at the amino acid level. |