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Publication : Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes.

First Author  Feng JQ Year  1994
Journal  Biochim Biophys Acta Volume  1218
Issue  2 Pages  221-4
PubMed ID  8018727 Mgi Jnum  J:18993
Mgi Id  MGI:67224 Doi  10.1016/0167-4781(94)90017-5
Citation  Feng JQ, et al. (1994) Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes. Biochim Biophys Acta 1218(2):221-4
abstractText  Screening of a mouse spleen genomic DNA library with mouse BMP-4 and BMP-2 cDNA probes led to the isolation of mouse BMP-2 gene. This gene contains approximately 11 kb transcription unit and 3 exons. The deduced protein has 394 amino acids. The C-terminal amino acid mature coding region is identical to that of the human BMP-2. Comparison of mouse BMP-2 and BMP-4 gene shows little similarity in exon/intron structure, although the mature coding peptide regions of both genes share over 90% identity at the amino acid level.
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