First Author | Horsley D | Year | 1996 |
Journal | Cytogenet Cell Genet | Volume | 73 |
Issue | 4 | Pages | 308-11 |
PubMed ID | 8751383 | Mgi Jnum | J:34920 |
Mgi Id | MGI:82375 | Doi | 10.1159/000134363 |
Citation | Horsley D, et al. (1996) M32, a murine homologue of Drosophila heterochromatin protein 1 (HP1), localises to euchromatin within interphase nuclei and is largely excluded from constitutive heterochromatin. Cytogenet Cell Genet 73(4):308-11 |
abstractText | Mice possess two structural homologues of Drosophila HP1, termed M31 and M32 (Singh et al., 1991). We have previously shown that an M31-specific monoclonal antibody (MoAb), MAC 353, localises to constitutive heterochromatin (Wreggett et al., 1994). Here we report that a MoAb raised against the M32 protein (MAC 385) recognises a 22-kDa protein in murine nuclear extracts and that M32 is distributed in a fine-grain speckled pattern within interphase nuclei. M32 is also largely excluded from the large masses of constitutive heterochromatin that are labelled by MAC 353. |