| First Author | Wu X | Year | 1995 |
| Journal | Biochem Biophys Res Commun | Volume | 216 |
| Issue | 1 | Pages | 78-83 |
| PubMed ID | 7488127 | Mgi Jnum | J:29643 |
| Mgi Id | MGI:77168 | Doi | 10.1006/bbrc.1995.2594 |
| Citation | Wu X, et al. (1995) Cloning and characterization of the murine activin receptor like kinase-1 (ALK-1) homolog. Biochem Biophys Res Commun 216(1):78-83 |
| abstractText | Multiple serine/threonine kinases were detected in a bone marrow stromal cell line. One of these, the murine activin receptor like kinase-1 (ALK-1) homolog was cloned and sequenced. The expressed recombinant protein (62 kDa) was consistent in size with that predicted by the cDNA (58.6 kDa). On Western blots, a goat polyclonal antibody detected the native ALK-1 protein in bone marrow stromal cells, lung, brain, kidney and spleen. Two protein species of 60 kDa and 72-76 kDa were detected. Glycosylation events or alternative splicing may account for the larger protein specie. |
