| First Author | Dobrosotskaya IY | Year | 2001 |
| Journal | Biochem Biophys Res Commun | Volume | 283 |
| Issue | 4 | Pages | 969-75 |
| PubMed ID | 11350080 | Mgi Jnum | J:200334 |
| Mgi Id | MGI:5508293 | Doi | 10.1006/bbrc.2001.4880 |
| Citation | Dobrosotskaya IY (2001) Identification of mNET1 as a candidate ligand for the first PDZ domain of MAGI-1. Biochem Biophys Res Commun 283(4):969-75 |
| abstractText | This paper reports the identification of a Rho family nucleotide exchange factor termed mNET1 as a candidate-interacting partner for the first PDZ domain of MAGI-1, a membrane-associated guanylate kinase with inverted arrangement of protein-protein interacting modules. mNET1 was identified in a yeast two-hybrid screen and has a consensus tripeptide for PDZ domain binding at its extreme carboxy-terminus. In addition to this sequence, a cluster of basic residues located near the carboxy terminus is essential for the binding. The interaction of the first PDZ domain of MAGI-1with mNET1 was documented using a variety of biochemical methods. |
