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Publication : Complete nucleotide sequence of the mouse lactate dehydrogenase-A functional gene: comparison of the exon-intron organization of dehydrogenase genes.

First Author  Fukasawa KM Year  1987
Journal  Genetics Volume  116
Issue  1 Pages  99-105
PubMed ID  3036647 Mgi Jnum  J:8748
Mgi Id  MGI:57213 Doi  10.1093/genetics/116.1.99
Citation  Fukasawa KM, et al. (1987) Complete nucleotide sequence of the mouse lactate dehydrogenase-A functional gene: comparison of the exon-intron organization of dehydrogenase genes. Genetics 116(1):99-105
abstractText  The complete sequence of 12,851 nucleotides of the mouse lactate dehydrogenase-A (LDH-A) gene has been determined. It includes eight exons, seven introns, promoter and regulatory regions. The B1 repetitive elements present in intron III and VI are oriented in opposite orientation, and they share 72% sequence homology. The exon-intron organization of mouse LDH-A gene is compared with the organizations of other dehydrogenase genes, and the molecular evolution of the nicotinamide adenine dinucleotide binding domains is discussed.
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