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Publication : Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors.

First Author  Tan CP Year  1998
Journal  Genomics Volume  52
Issue  2 Pages  223-9
PubMed ID  9782091 Mgi Jnum  J:50329
Mgi Id  MGI:1303172 Doi  10.1006/geno.1998.5441
Citation  Tan CP, et al. (1998) Cloning and characterization of a human and murine T-cell orphan G-protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors. Genomics 52(2):223-9
abstractText  Growth hormone secretagogues (GHS) are a group of synthetic peptide and nonpeptide molecules that potently stimulate the release of GH from the anterior pituitary gland through the activation of a novel G-protein-coupled receptor (GPC-R), the GHS-R. In our search for GHS-R family members, we recently described the cloning of two related GPC-Rs, GPR38 and 39. In the present report, we detail the isolation of a new GPC-R (FM-3) from human and mouse with moderate sequence identity to both the GHS-R and neurotensin-R. FM-3 is expressed in a diverse set of tissues. Copyright 1998 Academic Press.
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