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Publication : Characteristics of the mouse genomic histamine H1 receptor gene.

First Author  Inoue I Year  1996
Journal  Genomics Volume  36
Issue  1 Pages  178-81
PubMed ID  8812432 Mgi Jnum  J:34932
Mgi Id  MGI:82387 Doi  10.1006/geno.1996.0441
Citation  Inoue I, et al. (1996) Characteristics of the mouse genomic histamine H1 receptor gene. Genomics 36(1):178-81
abstractText  We report here the molecular cloning of a mouse histamine H1 receptor gene. The protein deduced from the nucleotide sequence is composed of 488 amino acid residues with characteristic properties of GTP binding protein-coupled receptors. Our results suggest that the mouse histamine H1 receptor gene is a single locus, and no related sequences were detected. Interspecific backcross analysis indicated that the mouse histamine H1 receptor gene (Hrh1) is located in the central region of mouse Chromosome 6 linked to microphthalmia (Mitfmi), ras-related fibrosarcoma oncogene 1 (Raf1), and ret proto-oncogene (Ret) in a region of homology with human chromosome 3p. (C) 1996 Academic Press, Inc.
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