First Author | Inoue I | Year | 1996 |
Journal | Genomics | Volume | 36 |
Issue | 1 | Pages | 178-81 |
PubMed ID | 8812432 | Mgi Jnum | J:34932 |
Mgi Id | MGI:82387 | Doi | 10.1006/geno.1996.0441 |
Citation | Inoue I, et al. (1996) Characteristics of the mouse genomic histamine H1 receptor gene. Genomics 36(1):178-81 |
abstractText | We report here the molecular cloning of a mouse histamine H1 receptor gene. The protein deduced from the nucleotide sequence is composed of 488 amino acid residues with characteristic properties of GTP binding protein-coupled receptors. Our results suggest that the mouse histamine H1 receptor gene is a single locus, and no related sequences were detected. Interspecific backcross analysis indicated that the mouse histamine H1 receptor gene (Hrh1) is located in the central region of mouse Chromosome 6 linked to microphthalmia (Mitfmi), ras-related fibrosarcoma oncogene 1 (Raf1), and ret proto-oncogene (Ret) in a region of homology with human chromosome 3p. (C) 1996 Academic Press, Inc. |