| First Author | Yamashita T | Year | 1998 |
| Journal | Genomics | Volume | 48 |
| Issue | 1 | Pages | 87-92 |
| PubMed ID | 9503020 | Mgi Jnum | J:46276 |
| Mgi Id | MGI:1197443 | Doi | 10.1006/geno.1997.5163 |
| Citation | Yamashita T, et al. (1998) Genomic structure and chromosomal localization of the mouse LIM domain-binding protein 1 gene, Ldb1. Genomics 48(1):87-92 |
| abstractText | The LIM domain is a structural motif that is well conserved throughout evolution in a variety of factors known to play important roles in development and cell regulation. Ldb genes encode LIM domain-binding (Ldb) factors. Here we report on the structural organization and chromosomal localization of the mouse Ldb1 gene. It contains at least 10 exons and spans approximately 4 kb of genomic DNA. The transcription initiation site is located 462 bp upstream of the translation initiation codon ATG: as determined by 5'-RACE. Sequencing analysis of the 5'- flanking region shows TATA and CCAAT motifs as well as potential binding sites for GATA, CF-1, PEA3, HRE, APRRE, RARE, Myc, and c-Jun. Ldb1 maps to the distal region of mouse chromosome 19 that is syntenic with human chromosome 10q. |
