| First Author | Alliel PM | Year | 2000 |
| Journal | Biochem Biophys Res Commun | Volume | 273 |
| Issue | 1 | Pages | 385-91 |
| PubMed ID | 10873615 | Mgi Jnum | J:62894 |
| Mgi Id | MGI:1860023 | Doi | 10.1006/bbrc.2000.2862 |
| Citation | Alliel PM, et al. (2000) Myoneurin, a novel member of the BTB/POZ-zinc finger family highly expressed in human muscle. Biochem Biophys Res Commun 273(1):385-91 |
| abstractText | Initially characterized as Drosophila developmental regulators, the BTB/POZ and zinc finger proteins (BTB/POZ-ZF) constitute a growing family of proteins with gene expression regulatory functions since they have been shown to be involved in both transcriptional activation and repression of various genes in a broad range of species, including mammals. Here we report the cloning of a novel human transcript, coding for a 68-kDa deduced BTB/POZ-ZF protein. This molecule, called myoneurin on the basis of its prevalent expression in the neuromuscular system, contains an amino-terminal BTB/POZ domain and eight tandemly repeated zinc-finger motifs of the C(2)H(2) type. The murine myoneurin, identified in the mouse embryo, is highly homologous to the human protein. Copyright 2000 Academic Press. |
