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Publication : Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

First Author  Nishioka Y Year  1980
Journal  J Biol Chem Volume  255
Issue  8 Pages  3691-4
PubMed ID  6767723 Mgi Jnum  J:27711
Mgi Id  MGI:75199 Doi  10.1016/s0021-9258(19)85759-9
Citation  Nishioka Y, et al. (1980) Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes. J Biol Chem 255(8):3691-4
abstractText  We have determined the entire sequence of two immunoglobulin kappa variable region genes derived separately from embryonic and plasmacytoma cells. Both genes are in the germline configuration; both are organized into hydrophobic leader and mature V-region coding sequences separated by a short intervening sequence. Both are identical with one another throughout the 1360 bases determined. In addition, there is a simple repeat sequence of 31 CA doublets that occurs about 300 bases from the 3' side of the coding sequence in each gene.
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